Tomato processing residues have been previously characterized from Rossini et al. (2013) by an energy perspective. Anaerobic GSK-LSD1 2HCl (AD) of agricultural by-products (e.g., animal slurry, food waste, food processing residues) have been recognized by several studies (Ward et al., 2008, Bacenetti et al., 2013, González-González et al., 2013, Lijó et al., 2014a, Lijó et al., 2014b and Ingrao et al., 2015) as a suitable and effective solution to produce renewable energy by means of a cogeneration systems (electricity — EE and thermal energy — TE). In Italy, thanks to the strong public incentives for electricity generation from biomass currently there are about 1150 AD plants (Negri et al., 2014a). Although most of these plants are fed with cereal silages (González-García et al., 2013, Lansche and Müller, 2012 and Bacenetti et al., 2014), after the revision of the subsidy framework the interest about small AD plants (electric power < 300 kW) fed with agricultural by-products and other wastes is increasing (Negri et al., 2014b).